Quilter is the most visible AI-native routing company. Its approach is physics-driven autonomous placement and routing delivered as a cloud service, and it accepts designs from Altium, Cadence, Siemens, and KiCad, which is a deliberate positioning choice, it wants to sit beside whatever you already use rather than replace it. There is a free tier for evaluating AI layout.
DeepPCB comes from InstaDeep, a company with deep reinforcement-learning expertise, and applies RL to cloud-native routing. Industry reporting has described it running thousands of real-world designs per week, which is the most concrete public signal that autonomous routing has moved past demonstration into routine production use for a class of boards. It offers a free tier and pay-as-you-go pricing and imports from the major EDA tools.
Both share the same structural constraint: they are cloud services, so every enterprise adoption conversation includes where proprietary design data goes and who can see it. And neither does schematic capture, so both need a capture tool upstream.